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21c Museum Hotel is more than just a place to rest your head for the night – it's a 90-room boutique hotel, contemporary art museum, and award-winning restaurant. The downtown Louisville hotel features friendly, personal service and thoughtful amenities, with a touch of luxury, that is sure to make you feel at home.
21c stands out among Louisville hotels as an artful alternative to the average. Applauded by Travel & Leisure magazine as “one of the most ambitious unions of art and hospitality ever undertaken,” come sleep with the iconic Red Penguins and experience how our Louisville boutique hotel is redefining the art of modern Southern hospitality.